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BDBM50041996 CHEMBL3359570

SMILES: Cl.CN1CCCN(CC1)c1ccc(cc1)C(=O)Nc1c(O)cccc1C(=O)Nc1ccc(Cl)cc1

InChI Key: InChIKey=RFBKISARJQOXAJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041996   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50041996
PNG
(CHEMBL3359570)
Show SMILES Cl.CN1CCCN(CC1)c1ccc(cc1)C(=O)Nc1c(O)cccc1C(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C26H27ClN4O3/c1-30-14-3-15-31(17-16-30)21-12-6-18(7-13-21)25(33)29-24-22(4-2-5-23(24)32)26(34)28-20-10-8-19(27)9-11-20/h2,4-13,32H,3,14-17H2,1H3,(H,28,34)(H,29,33)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 6.90n/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate reader


Bioorg Med Chem 23: 277-89 (2015)


Article DOI: 10.1016/j.bmc.2014.11.042
BindingDB Entry DOI: 10.7270/Q2P55Q4X
More data for this
Ligand-Target Pair