BDBM50042571 2-Benzyl-5-butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2H-pyrazole-3-carboxylic acid::CHEMBL433646

SMILES: CCCCc1nn(Cc2ccccc2)c(C(O)=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key: InChIKey=CHJNTVVKAIMAEW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50042571   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50042571 (2-Benzyl-5-butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...) Show SMILES CCCCc1nn(Cc2ccccc2)c(C(O)=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C29H28N6O2/c1-2-3-13-26-25(27(29(36)37)35(32-26)19-21-9-5-4-6-10-21)18-20-14-16-22(17-15-20)23-11-7-8-12-24(23)28-30-33-34-31-28/h4-12,14-17H,2-3,13,18-19H2,1H3,(H,36,37)(H,30,31,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Evaluation of Angiotensin II antagonistic activity by displacement of [125I]-Sar Ile-AII at the rabbit aorta Angiotensin II receptor, type 1				J Med Chem 36: 3595-605 (1994) BindingDB Entry DOI: 10.7270/Q25Q4V5H
					More data for this Ligand-Target Pair