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BDBM50042720 3-(5-Methyl-1H-imidazol-4-yl)-1-(4,5,6,7-tetrahydro-azepino[3,2,1-hi]indol-1-yl)-propan-1-one::CHEMBL421424

SMILES: Cc1nc[nH]c1CCC(=O)c1cn2CCCCc3cccc1c23

InChI Key: InChIKey=ILOKFFOBOKCGBT-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50042720   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)		BDBM50042720
PNG
(3-(5-Methyl-1H-imidazol-4-yl)-1-(4,5,6,7-tetrahydr...)
Show SMILES Cc1nc[nH]c1CCC(=O)c1cn2CCCCc3cccc1c23
Show InChI InChI=1S/C19H21N3O/c1-13-17(21-12-20-13)8-9-18(23)16-11-22-10-3-2-5-14-6-4-7-15(16)19(14)22/h4,6-7,11-12H,2-3,5,8-10H2,1H3,(H,20,21)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 0.330n/an/an/an/an/an/an/an/a



Solvay Duphar B.V.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was measured on muscarine M1 receptor using [3H]- pirenzepine as radioligand.

J Med Chem 36: 3693-9 (1994)


BindingDB Entry DOI: 10.7270/Q2NS0SZH
More data for this
Ligand-Target Pair