BDBM50042741 CHEMBL331797::[4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-(4-phenoxy-phenyl)-acetic acid

SMILES: CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(O)=O)c1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=IGOWKCVUJOXVRU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042741   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT2 (RAT)	BDBM50042741 (CHEMBL331797 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,...) Show SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(O)=O)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C37H41N3O4/c1-6-12-28-21-26(23-40-32(8-3)39-33-24(4)20-25(5)38-36(33)40)22-29(13-7-2)34(28)44-35(37(41)42)27-16-18-31(19-17-27)43-30-14-10-9-11-15-30/h9-11,14-22,35H,6-8,12-13,23H2,1-5H3,(H,41,42)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [1251][Sar1,IIe8]AII from rat midbrain angiotensin II (AT2) receptor				J Med Chem 36: 3738-42 (1994) BindingDB Entry DOI: 10.7270/Q2J1027W
					More data for this Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50042741 (CHEMBL331797 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,...) Show SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(O)=O)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C37H41N3O4/c1-6-12-28-21-26(23-40-32(8-3)39-33-24(4)20-25(5)38-36(33)40)22-29(13-7-2)34(28)44-35(37(41)42)27-16-18-31(19-17-27)43-30-14-10-9-11-15-30/h9-11,14-22,35H,6-8,12-13,23H2,1-5H3,(H,41,42)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [1251][Sar1,IIe8]AII from rabbit aorta Angiotensin II receptor, type 1				J Med Chem 36: 3738-42 (1994) BindingDB Entry DOI: 10.7270/Q2J1027W
					More data for this Ligand-Target Pair