BDBM50042759 CHEMBL125289::H-Tyr-D-Ala-His-Asp-Val-Val-Gly-NH2
SMILES: CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O
InChI Key: InChIKey=KPKLKHNZIHLGRE-GIIACPISSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Opioid receptors; mu & delta (Rattus norvegicus (rat)) | BDBM50042759 (CHEMBL125289 | H-Tyr-D-Ala-His-Asp-Val-Val-Gly-NH2) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ferrara Curated by ChEMBL | Assay Description Binding affinity was determined on delta [3H]-DPDPE site in rat brain synaptosomes by radioreceptor assay | J Med Chem 36: 3748-56 (1994) BindingDB Entry DOI: 10.7270/Q2D799HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50042759 (CHEMBL125289 | H-Tyr-D-Ala-His-Asp-Val-Val-Gly-NH2) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ferrara Curated by ChEMBL | Assay Description Binding affinity was determined on mu [3H]-DAGO site in rat brain synaptosomes by radioreceptor assay | J Med Chem 36: 3748-56 (1994) BindingDB Entry DOI: 10.7270/Q2D799HM | |||||||||||
More data for this Ligand-Target Pair |