BDBM50042953 3-(3,4-Dihydroxy-phenyl)-1-(5-isopropoxy-2-methoxy-phenyl)-propenone::CHEMBL126252

SMILES: COc1ccc(OC(C)C)cc1C(=O)\C=C\c1ccc(O)c(O)c1

InChI Key: InChIKey=IPRFNLJZHHMLQI-QPJJXVBHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50042953   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042953 (3-(3,4-Dihydroxy-phenyl)-1-(5-isopropoxy-2-methoxy...) Show SMILES COc1ccc(OC(C)C)cc1C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C19H20O5/c1-12(2)24-14-6-9-19(23-3)15(11-14)16(20)7-4-13-5-8-17(21)18(22)10-13/h4-12,21-22H,1-3H3/b7-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair