BDBM50042965 3-(3,4-Dihydroxy-phenyl)-1-(2-pyridin-3-yl-phenyl)-propenone::CHEMBL338169

SMILES: Oc1ccc(\C=C\C(=O)c2ccccc2-c2cccnc2)cc1O

InChI Key: InChIKey=JAKAHTATZJQAHM-VQHVLOKHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50042965   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042965 (3-(3,4-Dihydroxy-phenyl)-1-(2-pyridin-3-yl-phenyl)...) Show SMILES Oc1ccc(\C=C\C(=O)c2ccccc2-c2cccnc2)cc1O Show InChI InChI=1S/C20H15NO3/c22-18(9-7-14-8-10-19(23)20(24)12-14)17-6-2-1-5-16(17)15-4-3-11-21-13-15/h1-13,23-24H/b9-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair