BDBM50042974 3-(3,4-Dihydroxy-phenyl)-1-(2-thiophen-2-yl-phenyl)-propenone::CHEMBL129644

SMILES: Oc1ccc(\C=C\C(=O)c2ccccc2-c2cccs2)cc1O

InChI Key: InChIKey=GEPLWPIXSCGFIM-VQHVLOKHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50042974   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042974 (3-(3,4-Dihydroxy-phenyl)-1-(2-thiophen-2-yl-phenyl...) Show SMILES Oc1ccc(\C=C\C(=O)c2ccccc2-c2cccs2)cc1O Show InChI InChI=1S/C19H14O3S/c20-16(9-7-13-8-10-17(21)18(22)12-13)14-4-1-2-5-15(14)19-6-3-11-23-19/h1-12,21-22H/b9-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair