BDBM50042984 3-(3,4-Dihydroxy-phenyl)-1-(2-trifluoromethyl-phenyl)-propenone::CHEMBL126774

SMILES: Oc1ccc(\C=C\C(=O)c2ccccc2C(F)(F)F)cc1O

InChI Key: InChIKey=TVNCZBWVGGYPTK-FNORWQNLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50042984   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042984 (3-(3,4-Dihydroxy-phenyl)-1-(2-trifluoromethyl-phen...) Show SMILES Oc1ccc(\C=C\C(=O)c2ccccc2C(F)(F)F)cc1O Show InChI InChI=1S/C16H11F3O3/c17-16(18,19)12-4-2-1-3-11(12)13(20)7-5-10-6-8-14(21)15(22)9-10/h1-9,21-22H/b7-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair