BDBM50042989 3-(3,4-Dihydroxy-phenyl)-1-(2,5-dimethyl-phenyl)-propenone::CHEMBL127064

SMILES: Cc1ccc(C)c(c1)C(=O)C=Cc1ccc(O)c(O)c1

InChI Key: InChIKey=HOXVMIIDYPVTNI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50042989   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042989 (3-(3,4-Dihydroxy-phenyl)-1-(2,5-dimethyl-phenyl)-p...) Show SMILES Cc1ccc(C)c(c1)C(=O)C=Cc1ccc(O)c(O)c1 |w:11.12| Show InChI InChI=1S/C17H16O3/c1-11-3-4-12(2)14(9-11)15(18)7-5-13-6-8-16(19)17(20)10-13/h3-10,19-20H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair