BDBM50042990 (E)-3-(3'',4''-Dihydroxyphenyl)-1-(3',4',5'-trimethoxyphenyl)prop-2-en-1-one::(E)-3-(3,4-Dihydroxy-phenyl)-1-(3,4,5-trimethoxy-phenyl)-propenone::3,4-dihydroxy-3',4',5'-trimethoxychalcone::3-(3,4-Dihydroxy-phenyl)-1-(3,4,5-trimethoxy-phenyl)-propenone::3-(3,4-dihydroxyphenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one::CHEMBL126617

SMILES: COc1cc(cc(OC)c1OC)C(=O)\C=C\c1ccc(O)c(O)c1

InChI Key: InChIKey=YRADLNGHQMLFDH-GQCTYLIASA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042990   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50042990 ((E)-3-(3'',4''-Dihydroxyphenyl)-1-(3',4',5'-trimet...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C18H18O6/c1-22-16-9-12(10-17(23-2)18(16)24-3)13(19)6-4-11-5-7-14(20)15(21)8-11/h4-10,20-21H,1-3H3/b6-4+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Salford Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of tubulin polymerization				J Med Chem 48: 457-65 (2005) Article DOI: 10.1021/jm049444m BindingDB Entry DOI: 10.7270/Q2416WKV
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042990 ((E)-3-(3'',4''-Dihydroxyphenyl)-1-(3',4',5'-trimet...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C18H18O6/c1-22-16-9-12(10-17(23-2)18(16)24-3)13(19)6-4-11-5-7-14(20)15(21)8-11/h4-10,20-21H,1-3H3/b6-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair