BDBM50042994 (2E)-3-(3,4-dihydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one::CHEMBL127409::trans-2',3,4,4',6'-pentahydroxychalcone

SMILES: Oc1cc(O)c(C(=O)\C=C\c2ccc(O)c(O)c2)c(O)c1

InChI Key: InChIKey=CRBYNQCDRNZCNX-DUXPYHPUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042994   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042994 ((2E)-3-(3,4-dihydroxyphenyl)-1-(2,4,6-trihydroxyph...) Show SMILES Oc1cc(O)c(C(=O)\C=C\c2ccc(O)c(O)c2)c(O)c1 Show InChI InChI=1S/C15H12O6/c16-9-6-13(20)15(14(21)7-9)11(18)4-2-8-1-3-10(17)12(19)5-8/h1-7,16-17,19-21H/b4-2+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 5-lipoxygenase in rat RBL1 cells				Citation and Details Article DOI: 10.1007/s00044-013-0745-7 BindingDB Entry DOI: 10.7270/Q22N53QB
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042994 ((2E)-3-(3,4-dihydroxyphenyl)-1-(2,4,6-trihydroxyph...) Show SMILES Oc1cc(O)c(C(=O)\C=C\c2ccc(O)c(O)c2)c(O)c1 Show InChI InChI=1S/C15H12O6/c16-9-6-13(20)15(14(21)7-9)11(18)4-2-8-1-3-10(17)12(19)5-8/h1-7,16-17,19-21H/b4-2+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair