BDBM50043473 CHEMBL335289::{Ethyl-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2-methyl-phenyl]-amino}-phenyl-acetic acid

SMILES: CCN(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1C

InChI Key: InChIKey=QDBQENPGIAWQQM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043473   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-2 angiotensin II receptor (RAT)	BDBM50043473 (CHEMBL335289 | {Ethyl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCN(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1C Show InChI InChI=1S/C28H32N4O2/c1-6-24-30-25-19(4)15-20(5)29-27(25)32(24)17-21-13-14-23(18(3)16-21)31(7-2)26(28(33)34)22-11-9-8-10-12-22/h8-16,26H,6-7,17H2,1-5H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043473 (CHEMBL335289 | {Ethyl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCN(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1C Show InChI InChI=1S/C28H32N4O2/c1-6-24-30-25-19(4)15-20(5)29-27(25)32(24)17-21-13-14-23(18(3)16-21)31(7-2)26(28(33)34)22-11-9-8-10-12-22/h8-16,26H,6-7,17H2,1-5H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair