null

SMILES: CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(C)C(C(O)=O)c1ccccc1

InChI Key: InChIKey=SLDCMEISYKBOIQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043475   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-2 angiotensin II receptor (RAT)	BDBM50043475 (CHEMBL135345 | {[4-(2-Ethyl-5,7-dimethyl-imidazo[4...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(C)C(C(O)=O)c1ccccc1 Show InChI InChI=1S/C26H28N4O2/c1-5-22-28-23-17(2)15-18(3)27-25(23)30(22)16-19-11-13-21(14-12-19)29(4)24(26(31)32)20-9-7-6-8-10-20/h6-15,24H,5,16H2,1-4H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043475 (CHEMBL135345 | {[4-(2-Ethyl-5,7-dimethyl-imidazo[4...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(C)C(C(O)=O)c1ccccc1 Show InChI InChI=1S/C26H28N4O2/c1-5-22-28-23-17(2)15-18(3)27-25(23)30(22)16-19-11-13-21(14-12-19)29(4)24(26(31)32)20-9-7-6-8-10-20/h6-15,24H,5,16H2,1-4H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair