BDBM50043477 CHEMBL135704::[4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2-methyl-phenylamino]-phenyl-acetic acid

SMILES: CCc1nc2c(C)cc(C)nc2n1Cc1ccc(NC(C(O)=O)c2ccccc2)c(C)c1

InChI Key: InChIKey=YZWCYHQBPSQNPQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043477   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT2 (RAT)	BDBM50043477 (CHEMBL135704 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(NC(C(O)=O)c2ccccc2)c(C)c1 Show InChI InChI=1S/C26H28N4O2/c1-5-22-29-23-17(3)13-18(4)27-25(23)30(22)15-19-11-12-21(16(2)14-19)28-24(26(31)32)20-9-7-6-8-10-20/h6-14,24,28H,5,15H2,1-4H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50043477 (CHEMBL135704 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(NC(C(O)=O)c2ccccc2)c(C)c1 Show InChI InChI=1S/C26H28N4O2/c1-5-22-29-23-17(3)13-18(4)27-25(23)30(22)15-19-11-12-21(16(2)14-19)28-24(26(31)32)20-9-7-6-8-10-20/h6-14,24,28H,5,15H2,1-4H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair