BDBM50043481 1-{1-[2-(4-Methyl-piperazin-1-yl)-2-oxo-ethyl]-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl}-3-m-tolyl-urea; hydrochloride::CHEMBL542967

SMILES: CN1CCN(CC1)C(=O)CN1c2ccccc2C(=NC(NC(=O)Nc2cccc(C)c2)C1=O)c1ccccc1

InChI Key: InChIKey=NMUMPNJUIHBZLZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043481   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50043481 (1-{1-[2-(4-Methyl-piperazin-1-yl)-2-oxo-ethyl]-2-o...) Show SMILES CN1CCN(CC1)C(=O)CN1c2ccccc2C(=NC(NC(=O)Nc2cccc(C)c2)C1=O)c1ccccc1 |c:19| Show InChI InChI=1S/C30H32N6O3/c1-21-9-8-12-23(19-21)31-30(39)33-28-29(38)36(20-26(37)35-17-15-34(2)16-18-35)25-14-7-6-13-24(25)27(32-28)22-10-4-3-5-11-22/h3-14,19,28H,15-18,20H2,1-2H3,(H2,31,33,39)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of binding of [125I]-CCK-8 to the cholecystokinin type B receptor				J Med Chem 36: 4276-92 (1994) BindingDB Entry DOI: 10.7270/Q22J6CH9
					More data for this Ligand-Target Pair
Cholecystokinin receptor (RAT)	BDBM50043481 (1-{1-[2-(4-Methyl-piperazin-1-yl)-2-oxo-ethyl]-2-o...) Show SMILES CN1CCN(CC1)C(=O)CN1c2ccccc2C(=NC(NC(=O)Nc2cccc(C)c2)C1=O)c1ccccc1 |c:19| Show InChI InChI=1S/C30H32N6O3/c1-21-9-8-12-23(19-21)31-30(39)33-28-29(38)36(20-26(37)35-17-15-34(2)16-18-35)25-14-7-6-13-24(25)27(32-28)22-10-4-3-5-11-22/h3-14,19,28H,15-18,20H2,1-2H3,(H2,31,33,39)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of binding of [125I]CCK-8 to cholecystokinin type A receptor in rat pancreatic tissue				J Med Chem 36: 4276-92 (1994) BindingDB Entry DOI: 10.7270/Q22J6CH9
					More data for this Ligand-Target Pair