BDBM50043503 CHEMBL135218::Diethylamino-acetic acid 2-[2-oxo-5-phenyl-3-(3-m-tolyl-ureido)-2,3-dihydro-benzo[e][1,4]diazepin-1-yl]-ethyl ester

SMILES: CCN(CC)CC(=O)OCCN1c2ccccc2C(=NC(NC(=O)Nc2cccc(C)c2)C1=O)c1ccccc1

InChI Key: InChIKey=RSOKAKNJZRWVOW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043503   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50043503 (CHEMBL135218 | Diethylamino-acetic acid 2-[2-oxo-5...) Show SMILES CCN(CC)CC(=O)OCCN1c2ccccc2C(=NC(NC(=O)Nc2cccc(C)c2)C1=O)c1ccccc1 |c:19| Show InChI InChI=1S/C31H35N5O4/c1-4-35(5-2)21-27(37)40-19-18-36-26-17-10-9-16-25(26)28(23-13-7-6-8-14-23)33-29(30(36)38)34-31(39)32-24-15-11-12-22(3)20-24/h6-17,20,29H,4-5,18-19,21H2,1-3H3,(H2,32,34,39)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of binding of [125I]-CCK-8 to the cholecystokinin type B receptor				J Med Chem 36: 4276-92 (1994) BindingDB Entry DOI: 10.7270/Q22J6CH9
					More data for this Ligand-Target Pair
Cholecystokinin receptor (RAT)	BDBM50043503 (CHEMBL135218 | Diethylamino-acetic acid 2-[2-oxo-5...) Show SMILES CCN(CC)CC(=O)OCCN1c2ccccc2C(=NC(NC(=O)Nc2cccc(C)c2)C1=O)c1ccccc1 |c:19| Show InChI InChI=1S/C31H35N5O4/c1-4-35(5-2)21-27(37)40-19-18-36-26-17-10-9-16-25(26)28(23-13-7-6-8-14-23)33-29(30(36)38)34-31(39)32-24-15-11-12-22(3)20-24/h6-17,20,29H,4-5,18-19,21H2,1-3H3,(H2,32,34,39)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of binding of [125I]CCK-8 to cholecystokinin type A receptor in rat pancreatic tissue				J Med Chem 36: 4276-92 (1994) BindingDB Entry DOI: 10.7270/Q22J6CH9
					More data for this Ligand-Target Pair