BDBM50043541 3-{3-[3-(3-Methoxy-phenyl)-ureido]-2-oxo-5-phenyl-2,3-dihydro-benzo[e][1,4]diazepin-1-yl}-propionic acid ethyl ester::CHEMBL136966

SMILES: CCOC(=O)CCN1c2ccccc2C(=NC(NC(=O)Nc2cccc(OC)c2)C1=O)c1ccccc1

InChI Key: InChIKey=WUFKOEJNDDCQJA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043541   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (RAT)	BDBM50043541 (3-{3-[3-(3-Methoxy-phenyl)-ureido]-2-oxo-5-phenyl-...) Show SMILES CCOC(=O)CCN1c2ccccc2C(=NC(NC(=O)Nc2cccc(OC)c2)C1=O)c1ccccc1 |c:15| Show InChI InChI=1S/C28H28N4O5/c1-3-37-24(33)16-17-32-23-15-8-7-14-22(23)25(19-10-5-4-6-11-19)30-26(27(32)34)31-28(35)29-20-12-9-13-21(18-20)36-2/h4-15,18,26H,3,16-17H2,1-2H3,(H2,29,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of binding of [125I]CCK-8 to cholecystokinin type A receptor in rat pancreatic tissue				J Med Chem 36: 4276-92 (1994) BindingDB Entry DOI: 10.7270/Q22J6CH9
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50043541 (3-{3-[3-(3-Methoxy-phenyl)-ureido]-2-oxo-5-phenyl-...) Show SMILES CCOC(=O)CCN1c2ccccc2C(=NC(NC(=O)Nc2cccc(OC)c2)C1=O)c1ccccc1 |c:15| Show InChI InChI=1S/C28H28N4O5/c1-3-37-24(33)16-17-32-23-15-8-7-14-22(23)25(19-10-5-4-6-11-19)30-26(27(32)34)31-28(35)29-20-12-9-13-21(18-20)36-2/h4-15,18,26H,3,16-17H2,1-2H3,(H2,29,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of binding of [125I]-CCK-8 to the cholecystokinin type B receptor				J Med Chem 36: 4276-92 (1994) BindingDB Entry DOI: 10.7270/Q22J6CH9
					More data for this Ligand-Target Pair