BDBM50043850 (E)-6-{4-[2-(Butane-1-sulfonylamino)-ethyl]-phenyl}-6-pyridin-3-yl-hex-5-enoic acid::CHEMBL415519

SMILES: CCCCS(=O)(=O)NCCc1ccc(cc1)C(=C/CCCC(O)=O)\c1cccnc1

InChI Key: InChIKey=TVMXSNRHWWGXFV-GZIVZEMBSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043850   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50043850 ((E)-6-{4-[2-(Butane-1-sulfonylamino)-ethyl]-phenyl...) Show SMILES CCCCS(=O)(=O)NCCc1ccc(cc1)C(=C/CCCC(O)=O)\c1cccnc1 Show InChI InChI=1S/C23H30N2O4S/c1-2-3-17-30(28,29)25-16-14-19-10-12-20(13-11-19)22(8-4-5-9-23(26)27)21-7-6-15-24-18-21/h6-8,10-13,15,18,25H,2-5,9,14,16-17H2,1H3,(H,26,27)/b22-8+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Karl Thomae GmbH Curated by ChEMBL					Assay Description Displacement of the high affinity radiolabeled ligand [3H]- SQ-29,548 from the PGH-2/TXA-2 receptor in human gel-filtered platelets.				J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4
					More data for this Ligand-Target Pair
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human))	BDBM50043850 ((E)-6-{4-[2-(Butane-1-sulfonylamino)-ethyl]-phenyl...) Show SMILES CCCCS(=O)(=O)NCCc1ccc(cc1)C(=C/CCCC(O)=O)\c1cccnc1 Show InChI InChI=1S/C23H30N2O4S/c1-2-3-17-30(28,29)25-16-14-19-10-12-20(13-11-19)22(8-4-5-9-23(26)27)21-7-6-15-24-18-21/h6-8,10-13,15,18,25H,2-5,9,14,16-17H2,1H3,(H,26,27)/b22-8+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Karl Thomae GmbH Curated by ChEMBL					Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets.				J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4
					More data for this Ligand-Target Pair