BDBM50043858 (E)-6-[4-(2-Benzenesulfonylamino-ethyl)-phenyl]-6-pyridin-3-yl-hex-5-enoic acid::CHEMBL126761

SMILES: OC(=O)CCC\C=C(/c1ccc(CCNS(=O)(=O)c2ccccc2)cc1)c1cccnc1

InChI Key: InChIKey=CPFQQGFWCIINTC-YSURURNPSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043858   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50043858 ((E)-6-[4-(2-Benzenesulfonylamino-ethyl)-phenyl]-6-...) Show SMILES OC(=O)CCC\C=C(/c1ccc(CCNS(=O)(=O)c2ccccc2)cc1)c1cccnc1 Show InChI InChI=1S/C25H26N2O4S/c28-25(29)11-5-4-10-24(22-7-6-17-26-19-22)21-14-12-20(13-15-21)16-18-27-32(30,31)23-8-2-1-3-9-23/h1-3,6-10,12-15,17,19,27H,4-5,11,16,18H2,(H,28,29)/b24-10+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Karl Thomae GmbH Curated by ChEMBL					Assay Description Displacement of the high affinity radiolabeled ligand [3H]- SQ-29,548 from the PGH-2/TXA-2 receptor in human gel-filtered platelets.				J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4
					More data for this Ligand-Target Pair
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human))	BDBM50043858 ((E)-6-[4-(2-Benzenesulfonylamino-ethyl)-phenyl]-6-...) Show SMILES OC(=O)CCC\C=C(/c1ccc(CCNS(=O)(=O)c2ccccc2)cc1)c1cccnc1 Show InChI InChI=1S/C25H26N2O4S/c28-25(29)11-5-4-10-24(22-7-6-17-26-19-22)21-14-12-20(13-15-21)16-18-27-32(30,31)23-8-2-1-3-9-23/h1-3,6-10,12-15,17,19,27H,4-5,11,16,18H2,(H,28,29)/b24-10+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Karl Thomae GmbH Curated by ChEMBL					Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets.				J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4
					More data for this Ligand-Target Pair