BDBM50043862 (E)-4-{4-[2-(4-Chloro-benzenesulfonylamino)-ethyl]-phenyl}-4-pyridin-3-yl-but-3-enoic acid::CHEMBL340504

SMILES: OC(=O)C\C=C(/c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1

InChI Key: InChIKey=LJZXVXGFHZARCP-SSDVNMTOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043862   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50043862 ((E)-4-{4-[2-(4-Chloro-benzenesulfonylamino)-ethyl]...) Show SMILES OC(=O)C\C=C(/c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 Show InChI InChI=1S/C23H21ClN2O4S/c24-20-7-9-21(10-8-20)31(29,30)26-15-13-17-3-5-18(6-4-17)22(11-12-23(27)28)19-2-1-14-25-16-19/h1-11,14,16,26H,12-13,15H2,(H,27,28)/b22-11+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Karl Thomae GmbH Curated by ChEMBL					Assay Description Displacement of the high affinity radiolabeled ligand [3H]- SQ-29,548 from the PGH-2/TXA-2 receptor in human gel-filtered platelets.				J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4
					More data for this Ligand-Target Pair
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human))	BDBM50043862 ((E)-4-{4-[2-(4-Chloro-benzenesulfonylamino)-ethyl]...) Show SMILES OC(=O)C\C=C(/c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 Show InChI InChI=1S/C23H21ClN2O4S/c24-20-7-9-21(10-8-20)31(29,30)26-15-13-17-3-5-18(6-4-17)22(11-12-23(27)28)19-2-1-14-25-16-19/h1-11,14,16,26H,12-13,15H2,(H,27,28)/b22-11+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Karl Thomae GmbH Curated by ChEMBL					Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets.				J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4
					More data for this Ligand-Target Pair