BDBM50043881 1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-pyridin-2-yl-piperazine::CHEMBL417421

SMILES: COc1ccc2C(CCCN3CCN(CC3)c3ccccn3)=CCCc2c1

InChI Key: InChIKey=YFQVEXXLLCTPSB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043881   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50043881 (1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...) Show SMILES COc1ccc2C(CCCN3CCN(CC3)c3ccccn3)=CCCc2c1 |c:23| Show InChI InChI=1S/C23H29N3O/c1-27-21-10-11-22-19(6-4-7-20(22)18-21)8-5-13-25-14-16-26(17-15-25)23-9-2-3-12-24-23/h2-3,6,9-12,18H,4-5,7-8,13-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	778	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Inhibition of binding of radioligand [3H]-spiroperidol to dopamine D2 receptor in rat striatal membranes				J Med Chem 37: 99-104 (1994) BindingDB Entry DOI: 10.7270/Q2NP23GP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50043881 (1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...) Show SMILES COc1ccc2C(CCCN3CCN(CC3)c3ccccn3)=CCCc2c1 |c:23| Show InChI InChI=1S/C23H29N3O/c1-27-21-10-11-22-19(6-4-7-20(22)18-21)8-5-13-25-14-16-26(17-15-25)23-9-2-3-12-24-23/h2-3,6,9-12,18H,4-5,7-8,13-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	63.6	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description In vitro ability of the compound to inhibit binding of radioligand [3H]-8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortex				J Med Chem 37: 99-104 (1994) BindingDB Entry DOI: 10.7270/Q2NP23GP
					More data for this Ligand-Target Pair