BDBM50043892 1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL8536

SMILES: COc1ccccc1N1CCN(CCCC2=CCCc3cccc(OC)c23)CC1

InChI Key: InChIKey=VMCRBYMNSSSNGZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043892   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50043892 (1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...) Show SMILES COc1ccccc1N1CCN(CCCC2=CCCc3cccc(OC)c23)CC1 |t:16| Show InChI InChI=1S/C25H32N2O2/c1-28-23-13-4-3-12-22(23)27-18-16-26(17-19-27)15-7-11-21-9-5-8-20-10-6-14-24(29-2)25(20)21/h3-4,6,9-10,12-14H,5,7-8,11,15-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	17.4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Inhibition of binding of radioligand [3H]-spiroperidol to dopamine D2 receptor in rat striatal membranes				J Med Chem 37: 99-104 (1994) BindingDB Entry DOI: 10.7270/Q2NP23GP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50043892 (1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...) Show SMILES COc1ccccc1N1CCN(CCCC2=CCCc3cccc(OC)c23)CC1 |t:16| Show InChI InChI=1S/C25H32N2O2/c1-28-23-13-4-3-12-22(23)27-18-16-26(17-19-27)15-7-11-21-9-5-8-20-10-6-14-24(29-2)25(20)21/h3-4,6,9-10,12-14H,5,7-8,11,15-19H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description In vitro ability of the compound to inhibit binding of radioligand [3H]-8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortex				J Med Chem 37: 99-104 (1994) BindingDB Entry DOI: 10.7270/Q2NP23GP
					More data for this Ligand-Target Pair