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SMILES: CC(N1CCN(Cc2ccc(cc2)-c2ccc(cc2)C(O)(C(F)(F)F)C(F)(F)F)CC1)c1ccncc1

InChI Key: InChIKey=DNTMCNBTTISIRL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044178   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))		BDBM50044178
PNG
(CHEMBL3313932)
Show SMILES CC(N1CCN(Cc2ccc(cc2)-c2ccc(cc2)C(O)(C(F)(F)F)C(F)(F)F)CC1)c1ccncc1
Show InChI InChI=1S/C27H27F6N3O/c1-19(21-10-12-34-13-11-21)36-16-14-35(15-17-36)18-20-2-4-22(5-3-20)23-6-8-24(9-7-23)25(37,26(28,29)30)27(31,32)33/h2-13,19,37H,14-18H2,1H3
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 430n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Displacement of [3H]T0901317 from human RoRc expressed in HepG2 cells by scintillation proximity binding assay

J Med Chem 57: 5871-92 (2014)


Article DOI: 10.1021/jm401901d
BindingDB Entry DOI: 10.7270/Q2M0473Z
More data for this
Ligand-Target Pair