BDBM50045261 CHEMBL3310833

SMILES: COc1cc2n(C3COC3)c(=O)[nH]c2cc1NS(=O)(=O)c1cccc(Cl)c1Cl

InChI Key: InChIKey=CXYNNGVMXXERRL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50045261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50045261 (CHEMBL3310833) Show SMILES COc1cc2n(C3COC3)c(=O)[nH]c2cc1NS(=O)(=O)c1cccc(Cl)c1Cl Show InChI InChI=1S/C17H15Cl2N3O5S/c1-26-14-6-13-11(20-17(23)22(13)9-7-27-8-9)5-12(14)21-28(24,25)15-4-2-3-10(18)16(15)19/h2-6,9,21H,7-8H2,1H3,(H,20,23)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR4 expressed in CHO cell membranes by [35S]-GTPgammaS radioligand competition assay				Bioorg Med Chem 22: 4298-311 (2014) Article DOI: 10.1016/j.bmc.2014.05.021 BindingDB Entry DOI: 10.7270/Q2Z60QQG
					More data for this Ligand-Target Pair