BDBM50045298 CHEMBL3310838

SMILES: COc1cc2n(C3CN(C3)C(C)=O)c(=O)[nH]c2cc1NS(=O)(=O)c1cccc(Cl)c1Cl

InChI Key: InChIKey=DTXHONUTWZTYJE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50045298   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (CCR4) (Homo sapiens (Human))	BDBM50045298 (CHEMBL3310838) Show SMILES COc1cc2n(C3CN(C3)C(C)=O)c(=O)[nH]c2cc1NS(=O)(=O)c1cccc(Cl)c1Cl Show InChI InChI=1S/C19H18Cl2N4O5S/c1-10(26)24-8-11(9-24)25-15-7-16(30-2)14(6-13(15)22-19(25)27)23-31(28,29)17-5-3-4-12(20)18(17)21/h3-7,11,23H,8-9H2,1-2H3,(H,22,27)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR4 expressed in CHO cell membranes by [35S]-GTPgammaS radioligand competition assay				Bioorg Med Chem 22: 4298-311 (2014) Article DOI: 10.1016/j.bmc.2014.05.021 BindingDB Entry DOI: 10.7270/Q2Z60QQG
					More data for this Ligand-Target Pair