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SMILES: NC1Nc2c(nc(N)[nH]c2=O)C1Cc1ccsc1

InChI Key: InChIKey=XGAPPXKWFKSYLM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50046238   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Purine nucleoside phosphorylase


(Bos taurus (bovine))		BDBM50046238
PNG
(2,8-Diamino-9-thiophen-3-ylmethyl-1,9-dihydro-puri...)
Show SMILES NC1Nc2c(nc(N)[nH]c2=O)C1Cc1ccsc1
Show InChI InChI=1S/C11H13N5OS/c12-9-6(3-5-1-2-18-4-5)7-8(14-9)10(17)16-11(13)15-7/h1-2,4,6,9,14H,3,12H2,(H3,13,15,16,17)
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PubMed
n/an/a 0.630n/an/an/an/an/an/a



BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphate

J Med Chem 36: 55-69 (1993)


BindingDB Entry DOI: 10.7270/Q2B27TCX
More data for this
Ligand-Target Pair