BDBM50046317 2-(3-Amino-2-mercapto-4-phenyl-butyrylamino)-4-methyl-pentanoic acid::CHEMBL70920
SMILES: CC(C)C[C@H](NC(=O)C(S)C(N)Cc1ccccc1)C(O)=O
InChI Key: InChIKey=CJBSSFSBUKZFOW-MOKVOYLWSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leukotriene A4 hydrolase (Homo sapiens (Human)) | BDBM50046317 (2-(3-Amino-2-mercapto-4-phenyl-butyrylamino)-4-met...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytes | J Med Chem 36: 211-20 (1993) BindingDB Entry DOI: 10.7270/Q2T152P3 | |||||||||||
More data for this Ligand-Target Pair |