BDBM50046842 3-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-pentanoylamino)-3-methyl-pentanoylamino]-3-hydroxy-6-methyl-heptanoylamino}-propionic acid ethyl ester::CHEMBL141544
SMILES: CCOC(=O)CCNC(=O)CC(O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)CC)C(C)CC
InChI Key: InChIKey=WHXVDJWSDYFSQV-JDIRNYGHSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cathepsin D (Bos taurus) | BDBM50046842 (3-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-penta...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D. | J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (ECE) (Rattus norvegicus (Rat)) | BDBM50046842 (3-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-penta...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane. | J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F | |||||||||||
More data for this Ligand-Target Pair |