BDBM50047017 (6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanone::6-methoxy-4-quinolyl-5-vinyl-1-azabicyclo[2.2.2]oct-2-ylmethanone::CHEMBL15477
SMILES: COc1ccc2nccc(C(=O)C3CC4CCN3CC4C=C)c2c1
InChI Key: InChIKey=SRFCUPVBYYAMIL-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50047017 ((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | 720 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut f£r Toxikologie Curated by ChEMBL | Assay Description Inhibitory effect on Bufuralol 1'-hydroxylation by human liver microsomes (Ki = apparent inhibition constant) | J Med Chem 36: 1136-45 (1993) BindingDB Entry DOI: 10.7270/Q2GM87X6 | |||||||||||
More data for this Ligand-Target Pair |