BDBM50047143 1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinolin-7-ol::BDBM50452346::CHEMBL24357::CHEMBL56519
SMILES: [H][C@]12CCc3c(O)cccc3[C@]1([H])CCCN2
InChI Key: InChIKey=RWDHALOKAOEZPC-KFJBMODSSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50047143![]() (1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinolin-7-ol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn Laboratories Curated by ChEMBL | Assay Description Compound was tested for agonistic activity against D2 receptor from cloned CHO cells, used [3H]U-86170 as radioligand | J Med Chem 36: 1301-15 (1993) BindingDB Entry DOI: 10.7270/Q2TD9Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50047143![]() (1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinolin-7-ol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn Laboratories Curated by ChEMBL | Assay Description Compound was tested for antagonistic activity against D2 receptor from rat striatum, used [3H]raclopride as radioligand | J Med Chem 36: 1301-15 (1993) BindingDB Entry DOI: 10.7270/Q2TD9Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50047143![]() (1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinolin-7-ol...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn Laboratories Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor from bovine hippocampus, used [3H]8-OH-DPAT as radioligand | J Med Chem 36: 1301-15 (1993) BindingDB Entry DOI: 10.7270/Q2TD9Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50047143![]() (1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinolin-7-ol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a | n/a |
University of G£teborg Curated by ChEMBL | Assay Description Binding affinity against Dopamine receptor D2 using [3H]spiperone as radioligand | J Med Chem 30: 2169-74 (1988) BindingDB Entry DOI: 10.7270/Q2MW2HQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50047143![]() (1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinolin-7-ol...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of G£teborg Curated by ChEMBL | Assay Description In vitro for binding affinity against sigma receptor using [3H](+)-3-PPP as radioligand | J Med Chem 30: 2169-74 (1988) BindingDB Entry DOI: 10.7270/Q2MW2HQJ | |||||||||||
More data for this Ligand-Target Pair |