BDBM50047376 (E)-3-Phenyl-1-(3,4,5-trimethoxy-phenyl)-propenone::(E)-3-phenyl-1-(3',4',5'-trimethoxyphenyl)-2-propen-1-one::3-Phenyl-1-(3,4,5-trimethoxy-phenyl)-propenone::3-phenyl-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one::CHEMBL32353
SMILES: COc1cc(cc(OC)c1OC)C(=O)\C=C\c1ccccc1
InChI Key: InChIKey=HJRVQVGPAQZDPJ-MDZDMXLPSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Angiotensin-converting enzyme (Oryctolagus cuniculus) | BDBM50047376![]() ((E)-3-Phenyl-1-(3,4,5-trimethoxy-phenyl)-propenone...) | MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.38E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calabria Curated by ChEMBL | Assay Description Inhibition of ACE in rabbit lung assessed as decrease in dansylglycine concentration after 5 mins by HPLC analysis | Bioorg Med Chem Lett 20: 1990-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.113 BindingDB Entry DOI: 10.7270/Q2G73DW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tumor necrosis factor receptor R1 (Homo sapiens (Human)) | BDBM50047376![]() ((E)-3-Phenyl-1-(3,4,5-trimethoxy-phenyl)-propenone...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AtheroGenics, Inc. Curated by ChEMBL | Assay Description Inhibition of TNF-alpha-induced VCAM-1 expression | Bioorg Med Chem Lett 14: 1513-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.021 BindingDB Entry DOI: 10.7270/Q2028QZK | |||||||||||
More data for this Ligand-Target Pair |