null

SMILES: CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccc(CCCC)cc2)cccc1N(C)C

InChI Key: InChIKey=KGLIRNVBEZUXJQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50047517   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047517 (1-(2-{3-[4-(4-Butyl-phenyl)-imidazol-1-yl]-propoxy...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccc(CCCC)cc2)cccc1N(C)C Show InChI InChI=1S/C30H43N5O2/c1-5-7-9-19-31-30(36)33-29-27(34(3)4)13-10-14-28(29)37-21-11-20-35-22-26(32-23-35)25-17-15-24(16-18-25)12-8-6-2/h10,13-18,22-23H,5-9,11-12,19-21H2,1-4H3,(H2,31,33,36)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit aorta homogenate.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047517 (1-(2-{3-[4-(4-Butyl-phenyl)-imidazol-1-yl]-propoxy...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccc(CCCC)cc2)cccc1N(C)C Show InChI InChI=1S/C30H43N5O2/c1-5-7-9-19-31-30(36)33-29-27(34(3)4)13-10-14-28(29)37-21-11-20-35-22-26(32-23-35)25-17-15-24(16-18-25)12-8-6-2/h10,13-18,22-23H,5-9,11-12,19-21H2,1-4H3,(H2,31,33,36)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair