BDBM50047528 1-[2-(3-Benzoimidazol-1-yl-propoxy)-6-dimethylamino-phenyl]-3-pentyl-urea::CHEMBL40516

SMILES: CCCCCNC(=O)Nc1c(OCCCn2cnc3ccccc23)cccc1N(C)C

InChI Key: InChIKey=AFXKWXLBLYFGRF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50047528   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047528 (1-[2-(3-Benzoimidazol-1-yl-propoxy)-6-dimethylamin...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc3ccccc23)cccc1N(C)C Show InChI InChI=1S/C24H33N5O2/c1-4-5-8-15-25-24(30)27-23-21(28(2)3)13-9-14-22(23)31-17-10-16-29-18-26-19-11-6-7-12-20(19)29/h6-7,9,11-14,18H,4-5,8,10,15-17H2,1-3H3,(H2,25,27,30)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047528 (1-[2-(3-Benzoimidazol-1-yl-propoxy)-6-dimethylamin...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc3ccccc23)cccc1N(C)C Show InChI InChI=1S/C24H33N5O2/c1-4-5-8-15-25-24(30)27-23-21(28(2)3)13-9-14-22(23)31-17-10-16-29-18-26-19-11-6-7-12-20(19)29/h6-7,9,11-14,18H,4-5,8,10,15-17H2,1-3H3,(H2,25,27,30)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit aorta homogenate.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair