BDBM50048301 4-[1-((R)-3-Phenyl-cyclohex-3-enylmethyl)-1,2,3,6-tetrahydro-pyridin-4-yl]-phenol::CHEMBL356269

SMILES: Oc1ccc(cc1)C1=CCN(C[C@@H]2CCC=C(C2)c2ccccc2)CC1

InChI Key: InChIKey=RIRRORJZVJGNAL-LJQANCHMSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50048301   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50048301 (4-[1-((R)-3-Phenyl-cyclohex-3-enylmethyl)-1,2,3,6-...) Show SMILES Oc1ccc(cc1)C1=CCN(C[C@@H]2CCC=C(C2)c2ccccc2)CC1 |c:16,t:8| Show InChI InChI=1S/C24H27NO/c26-24-11-9-21(10-12-24)22-13-15-25(16-14-22)18-19-5-4-8-23(17-19)20-6-2-1-3-7-20/h1-3,6-13,19,26H,4-5,14-18H2/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity of the compound towards human Dopamine receptor D2L evaluated using [3H]-N-0437				J Med Chem 38: 5007-14 (1996) BindingDB Entry DOI: 10.7270/Q2VQ31SG
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50048301 (4-[1-((R)-3-Phenyl-cyclohex-3-enylmethyl)-1,2,3,6-...) Show SMILES Oc1ccc(cc1)C1=CCN(C[C@@H]2CCC=C(C2)c2ccccc2)CC1 |c:16,t:8| Show InChI InChI=1S/C24H27NO/c26-24-11-9-21(10-12-24)22-13-15-25(16-14-22)18-19-5-4-8-23(17-19)20-6-2-1-3-7-20/h1-3,6-13,19,26H,4-5,14-18H2/t19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	56.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity of the compound towards human Dopamine receptor D3 evaluated using [3H]-spiperone				J Med Chem 38: 5007-14 (1996) BindingDB Entry DOI: 10.7270/Q2VQ31SG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50048301 (4-[1-((R)-3-Phenyl-cyclohex-3-enylmethyl)-1,2,3,6-...) Show SMILES Oc1ccc(cc1)C1=CCN(C[C@@H]2CCC=C(C2)c2ccccc2)CC1 |c:16,t:8| Show InChI InChI=1S/C24H27NO/c26-24-11-9-21(10-12-24)22-13-15-25(16-14-22)18-19-5-4-8-23(17-19)20-6-2-1-3-7-20/h1-3,6-13,19,26H,4-5,14-18H2/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity of the compound towards human Dopamine receptor D2L evaluated using [3H]-spiperone				J Med Chem 38: 5007-14 (1996) BindingDB Entry DOI: 10.7270/Q2VQ31SG
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50048301 (4-[1-((R)-3-Phenyl-cyclohex-3-enylmethyl)-1,2,3,6-...) Show SMILES Oc1ccc(cc1)C1=CCN(C[C@@H]2CCC=C(C2)c2ccccc2)CC1 |c:16,t:8| Show InChI InChI=1S/C24H27NO/c26-24-11-9-21(10-12-24)22-13-15-25(16-14-22)18-19-5-4-8-23(17-19)20-6-2-1-3-7-20/h1-3,6-13,19,26H,4-5,14-18H2/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity of the compound towards human Dopamine receptor D4.2 evaluated using [3H]-spiperone				J Med Chem 38: 5007-14 (1996) BindingDB Entry DOI: 10.7270/Q2VQ31SG
					More data for this Ligand-Target Pair