BDBM50048386 1-(4-aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepine::5-(4-Amino-phenyl)-8-methyl-8,9-dihydro-1,3-dioxa-6,7-diaza-cyclohepta[f]indene-7-carboxylic acid methylamide::CHEMBL267450

SMILES: CNC(=O)N1N=C(c2ccc(N)cc2)c2cc3OCOc3cc2CC1C

InChI Key: InChIKey=SMGACXZFVXKEAX-UHFFFAOYSA-N

Data: 2 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50048386   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GRIA2 (Homo sapiens (Human))	BDBM50048386 (1-(4-aminophenyl)-3-methylcarbamyl-4-methyl-3,4-di...) Show SMILES CNC(=O)N1N=C(c2ccc(N)cc2)c2cc3OCOc3cc2CC1C |t:5| Show InChI InChI=1S/C19H20N4O3/c1-11-7-13-8-16-17(26-10-25-16)9-15(13)18(22-23(11)19(24)21-2)12-3-5-14(20)6-4-12/h3-6,8-9,11H,7,10,20H2,1-2H3,(H,21,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activity at recombinant GluA2 receptor flip isoform expressed in Xenopus oocytes co-expressing gamma2-TARP assessed as effect on glutamate/trichlorom...				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
					More data for this Ligand-Target Pair				3D Structure (crystal)
GRIA1 (Homo sapiens (Human))	BDBM50048386 (1-(4-aminophenyl)-3-methylcarbamyl-4-methyl-3,4-di...) Show SMILES CNC(=O)N1N=C(c2ccc(N)cc2)c2cc3OCOc3cc2CC1C |t:5| Show InChI InChI=1S/C19H20N4O3/c1-11-7-13-8-16-17(26-10-25-16)9-15(13)18(22-23(11)19(24)21-2)12-3-5-14(20)6-4-12/h3-6,8-9,11H,7,10,20H2,1-2H3,(H,21,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activity at recombinant GluA1 receptor flip isoform expressed in Xenopus oocytes co-expressing gamma2-TARP assessed as effect on glutamate/trichlorom...				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
					More data for this Ligand-Target Pair