BDBM50048871 1-[4-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-butyl]-4-(3,4,5,6-tetrahydro-pyridin-2-yl)-piperazine::CHEMBL50239

SMILES: COc1cccc2C(CCCCN3CCN(CC3)C3=NCCCC3)CCCc12

InChI Key: InChIKey=ZJMAZGLYVRKYRY-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50048871   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50048871 (1-[4-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1cccc2C(CCCCN3CCN(CC3)C3=NCCCC3)CCCc12 |t:19| Show InChI InChI=1S/C24H37N3O/c1-28-23-12-7-10-21-20(9-6-11-22(21)23)8-3-5-15-26-16-18-27(19-17-26)24-13-2-4-14-25-24/h7,10,12,20H,2-6,8-9,11,13-19H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from rat hippocampal 5-hydroxytryptamine 1A receptor with 10e-6 M ketanserin				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50048871 (1-[4-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1cccc2C(CCCCN3CCN(CC3)C3=NCCCC3)CCCc12 |t:19| Show InChI InChI=1S/C24H37N3O/c1-28-23-12-7-10-21-20(9-6-11-22(21)23)8-3-5-15-26-16-18-27(19-17-26)24-13-2-4-14-25-24/h7,10,12,20H,2-6,8-9,11,13-19H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]DTG binding to sigma receptor from guinea pig brain cortex membrane				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50048871 (1-[4-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1cccc2C(CCCCN3CCN(CC3)C3=NCCCC3)CCCc12 |t:19| Show InChI InChI=1S/C24H37N3O/c1-28-23-12-7-10-21-20(9-6-11-22(21)23)8-3-5-15-26-16-18-27(19-17-26)24-13-2-4-14-25-24/h7,10,12,20H,2-6,8-9,11,13-19H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	396	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibitory activity against Sigma opioid receptor type 1 isolated from whole rat membranes using [3H](+)-pentazocine as radioligand.				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
NMDA receptor subunit 2C (GluN2C) (Rattus norvegicus (Rat))	BDBM50048871 (1-[4-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1cccc2C(CCCCN3CCN(CC3)C3=NCCCC3)CCCc12 |t:19| Show InChI InChI=1S/C24H37N3O/c1-28-23-12-7-10-21-20(9-6-11-22(21)23)8-3-5-15-26-16-18-27(19-17-26)24-13-2-4-14-25-24/h7,10,12,20H,2-6,8-9,11,13-19H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.33E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using PCP as radioligand at a concentration of 10e-5 M				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair