BDBM50048957 4'-((R)-2-Amino-3-mercapto-propionylamino)-biphenyl-3-carboxylic acid::CHEMBL71370
SMILES: N[C@@H](CS)C(=O)Nc1ccc(cc1)-c1cccc(c1)C(O)=O
InChI Key: InChIKey=FLFJJCYCOPXMEA-AWEZNQCLSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT) (Homo sapiens (Human)) | BDBM50048957 (4'-((R)-2-Amino-3-mercapto-propionylamino)-bipheny...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description In vitro inhibition of Geranylgeranyl transferase type I | J Med Chem 39: 217-23 (1996) Article DOI: 10.1021/jm950414g BindingDB Entry DOI: 10.7270/Q23J3DM7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein Farnesyltransferase (PFT) (Homo sapiens (Human)) | BDBM50048957 (4'-((R)-2-Amino-3-mercapto-propionylamino)-bipheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description In vitro inhibition of Farnesyltransferase | J Med Chem 39: 217-23 (1996) Article DOI: 10.1021/jm950414g BindingDB Entry DOI: 10.7270/Q23J3DM7 | |||||||||||
More data for this Ligand-Target Pair |