BDBM50048976 (S)-2-({2-[(S)-2-((R)-2-Amino-3-mercapto-propionylamino)-3-methyl-butyrylamino]-indane-2-carbonyl}-amino)-4-methylsulfanyl-butyric acid::CHEMBL308283

SMILES: CSCC[C@H](NC(=O)C1(Cc2ccccc2C1)NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(O)=O

InChI Key: InChIKey=REZJOXXWQFILST-BZSNNMDCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50048976   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) Chain B (Homo sapiens (Human))	BDBM50048976 ((S)-2-({2-[(S)-2-((R)-2-Amino-3-mercapto-propionyl...) Show SMILES CSCC[C@H](NC(=O)C1(Cc2ccccc2C1)NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(O)=O Show InChI InChI=1S/C23H34N4O5S2/c1-13(2)18(26-19(28)16(24)12-33)20(29)27-23(10-14-6-4-5-7-15(14)11-23)22(32)25-17(21(30)31)8-9-34-3/h4-7,13,16-18,33H,8-12,24H2,1-3H3,(H,25,32)(H,26,28)(H,27,29)(H,30,31)/t16-,17-,18-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory activity against Farnesyltransferase				J Med Chem 39: 224-36 (1996) Article DOI: 10.1021/jm950642a BindingDB Entry DOI: 10.7270/Q2610ZDS
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