BDBM50048995 CHEMBL82325::N-Hydroxy-N-methyl-2-(11-oxo-6,11-dihydro-dibenzo[b,e]oxepin-2-yl)-propionamide

SMILES: CC(C(=O)N(C)O)c1ccc2OCc3ccccc3C(=O)c2c1

InChI Key: InChIKey=GXPVTRYNVKFRPA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50048995   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50048995 (CHEMBL82325 | N-Hydroxy-N-methyl-2-(11-oxo-6,11-di...) Show SMILES CC(C(=O)N(C)O)c1ccc2OCc3ccccc3C(=O)c2c1 Show InChI InChI=1S/C18H17NO4/c1-11(18(21)19(2)22)12-7-8-16-15(9-12)17(20)14-6-4-3-5-13(14)10-23-16/h3-9,11,22H,10H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatant				J Med Chem 39: 246-52 (1996) Article DOI: 10.1021/jm950563z BindingDB Entry DOI: 10.7270/Q22806PF
					More data for this Ligand-Target Pair