BDBM50049525 CHEMBL3317479

SMILES: COc1ccc(cc1F)-c1nc(ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1)C(F)(F)F

InChI Key: InChIKey=XCCVLMJETQIWTD-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049525   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50049525 (CHEMBL3317479) Show SMILES COc1ccc(cc1F)-c1nc(ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1)C(F)(F)F Show InChI InChI=1S/C24H22F5N3O4S/c1-13(14-4-7-19(17(25)10-14)32-37(3,34)35)23(33)30-12-16-6-9-21(24(27,28)29)31-22(16)15-5-8-20(36-2)18(26)11-15/h4-11,13,32H,12H2,1-3H3,(H,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity against human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced channel activation by FLIPR assay				Bioorg Med Chem Lett 24: 4044-7 (2014) Article DOI: 10.1016/j.bmcl.2014.05.072 BindingDB Entry DOI: 10.7270/Q2JH3NTH
					More data for this Ligand-Target Pair