BDBM50049542 CHEMBL3317491

SMILES: CC(C(=O)NCc1ccc(nc1-c1ccc2cc[nH]c2c1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1

InChI Key: InChIKey=JCUYVMYIZDQZHG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049542   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50049542 (CHEMBL3317491) Show SMILES CC(C(=O)NCc1ccc(nc1-c1ccc2cc[nH]c2c1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C25H22F4N4O3S/c1-14(16-5-7-20(19(26)11-16)33-37(2,35)36)24(34)31-13-18-6-8-22(25(27,28)29)32-23(18)17-4-3-15-9-10-30-21(15)12-17/h3-12,14,30,33H,13H2,1-2H3,(H,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity against human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced channel activation by FLIPR assay				Bioorg Med Chem Lett 24: 4044-7 (2014) Article DOI: 10.1016/j.bmcl.2014.05.072 BindingDB Entry DOI: 10.7270/Q2JH3NTH
					More data for this Ligand-Target Pair