BDBM50049633 3-Chloro-4-fluoro-[1,1'';2'',1'''']terphenyl-4''''-sulfonic acid amide::3-Chloro-4-fluoro-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL54412

SMILES: NS(=O)(=O)c1ccc(cc1)-c1ccccc1-c1ccc(F)c(Cl)c1

InChI Key: InChIKey=BRWDKJBTMKFKLU-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50049633   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50049633 (3-Chloro-4-fluoro-[1,1'';2'',1'''']terphenyl-4''''...) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1ccccc1-c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C18H13ClFNO2S/c19-17-11-13(7-10-18(17)20)16-4-2-1-3-15(16)12-5-8-14(9-6-12)24(21,22)23/h1-11H,(H2,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 1.				J Med Chem 39: 1846-56 (1996) Article DOI: 10.1021/jm950878e BindingDB Entry DOI: 10.7270/Q2Z89BGW
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50049633 (3-Chloro-4-fluoro-[1,1'';2'',1'''']terphenyl-4''''...) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1ccccc1-c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C18H13ClFNO2S/c19-17-11-13(7-10-18(17)20)16-4-2-1-3-15(16)12-5-8-14(9-6-12)24(21,22)23/h1-11H,(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2				J Med Chem 39: 1846-56 (1996) Article DOI: 10.1021/jm950878e BindingDB Entry DOI: 10.7270/Q2Z89BGW
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50049633 (3-Chloro-4-fluoro-[1,1'';2'',1'''']terphenyl-4''''...) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1ccccc1-c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C18H13ClFNO2S/c19-17-11-13(7-10-18(17)20)16-4-2-1-3-15(16)12-5-8-14(9-6-12)24(21,22)23/h1-11H,(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	17.0	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lille 2 Curated by ChEMBL					Assay Description Inhibition of human Prostaglandin G/H synthase 2				J Med Chem 44: 3223-30 (2001) BindingDB Entry DOI: 10.7270/Q2736S4D
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50049633 (3-Chloro-4-fluoro-[1,1'';2'',1'''']terphenyl-4''''...) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1ccccc1-c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C18H13ClFNO2S/c19-17-11-13(7-10-18(17)20)16-4-2-1-3-15(16)12-5-8-14(9-6-12)24(21,22)23/h1-11H,(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Binding affinity for Prostaglandin G/H synthase 2 (COX-2)				Bioorg Med Chem Lett 14: 4665-70 (2004) Article DOI: 10.1016/j.bmcl.2004.06.095 BindingDB Entry DOI: 10.7270/Q2Q23ZQZ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50049633 (3-Chloro-4-fluoro-[1,1'';2'',1'''']terphenyl-4''''...) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1ccccc1-c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C18H13ClFNO2S/c19-17-11-13(7-10-18(17)20)16-4-2-1-3-15(16)12-5-8-14(9-6-12)24(21,22)23/h1-11H,(H2,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Binding affinity for Prostaglandin G/H synthase 1 (COX-1)				Bioorg Med Chem Lett 14: 4665-70 (2004) Article DOI: 10.1016/j.bmcl.2004.06.095 BindingDB Entry DOI: 10.7270/Q2Q23ZQZ
					More data for this Ligand-Target Pair