BDBM50049917 CHEMBL3322415

SMILES: NS(=O)(=O)c1ccc(cc1)N1CCN=C1c1cccc(Cl)c1

InChI Key: InChIKey=ZZKLXJXTFZOFCI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049917   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50049917 (CHEMBL3322415) Show SMILES NS(=O)(=O)c1ccc(cc1)N1CCN=C1c1cccc(Cl)c1 |c:14| Show InChI InChI=1S/C15H14ClN3O2S/c16-12-3-1-2-11(10-12)15-18-8-9-19(15)13-4-6-14(7-5-13)22(17,20)21/h1-7,10H,8-9H2,(H2,17,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay				Eur J Med Chem 84: 160-72 (2014) Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT
					More data for this Ligand-Target Pair