BDBM50049933 CHEMBL3317690

SMILES: Cc1cc2c3cnccc3cc(CCc3nc4ccccc4n3C)n2n1

InChI Key: InChIKey=PIJWWJLVISVNPQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049933   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50049933 (CHEMBL3317690) Show SMILES Cc1cc2c3cnccc3cc(CCc3nc4ccccc4n3C)n2n1 Show InChI InChI=1S/C21H19N5/c1-14-11-20-17-13-22-10-9-15(17)12-16(26(20)24-14)7-8-21-23-18-5-3-4-6-19(18)25(21)2/h3-6,9-13H,7-8H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Sassari Curated by ChEMBL					Assay Description Inhibition of human PDE10A (amino acids 14 to 779) using [3H]-labelled cyclic nucleotide as substrate after 1 hr b beta counting				Eur J Med Chem 84: 181-93 (2014) Article DOI: 10.1016/j.ejmech.2014.07.020 BindingDB Entry DOI: 10.7270/Q2S1844K
					More data for this Ligand-Target Pair