BDBM50050177 (2-Iodo-phenyl)-carbamic acid 3-(1H-imidazol-4-yl)-propyl ester::CHEMBL282688

SMILES: Ic1ccccc1NC(=O)OCCCc1cnc[nH]1

InChI Key: InChIKey=YUXJXDWPSOOOBN-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50050177   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50050177 ((2-Iodo-phenyl)-carbamic acid 3-(1H-imidazol-4-yl)...) Show SMILES Ic1ccccc1NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C13H14IN3O2/c14-11-5-1-2-6-12(11)17-13(18)19-7-3-4-10-8-15-9-16-10/h1-2,5-6,8-9H,3-4,7H2,(H,15,16)(H,17,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description In vitro antagonistic activity tested against Histamine H3 receptor on synaptosomes from rat cerebral cortex				J Med Chem 39: 1220-6 (1996) Article DOI: 10.1021/jm9504767 BindingDB Entry DOI: 10.7270/Q28K7855
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50050177 ((2-Iodo-phenyl)-carbamic acid 3-(1H-imidazol-4-yl)...) Show SMILES Ic1ccccc1NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C13H14IN3O2/c14-11-5-1-2-6-12(11)17-13(18)19-7-3-4-10-8-15-9-16-10/h1-2,5-6,8-9H,3-4,7H2,(H,15,16)(H,17,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description In vitro antagonistic activity tested against Histamine H3 receptor on synaptosomes from rat cerebral cortex				J Med Chem 39: 1220-6 (1996) Article DOI: 10.1021/jm9504767 BindingDB Entry DOI: 10.7270/Q28K7855
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50050177 ((2-Iodo-phenyl)-carbamic acid 3-(1H-imidazol-4-yl)...) Show SMILES Ic1ccccc1NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C13H14IN3O2/c14-11-5-1-2-6-12(11)17-13(18)19-7-3-4-10-8-15-9-16-10/h1-2,5-6,8-9H,3-4,7H2,(H,15,16)(H,17,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	25.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Binding affinity towards Histamine H3 receptor on synaptosomes from rat cerebral cortex				J Med Chem 39: 1220-6 (1996) Article DOI: 10.1021/jm9504767 BindingDB Entry DOI: 10.7270/Q28K7855
					More data for this Ligand-Target Pair