BDBM50051195 (2-ferrocenyl)-carbamic acid 3-(1H-imidazol-4-yl)-propylester: C4H4O40.25H2O::CHEMBL280249
SMILES: O=C(NCC1=CC=CC1[Fe++]C1C=CC=C1)OCCCc1cnc[nH]1
InChI Key: InChIKey=LMSKOPWWMURUCE-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H3 receptor (Rattus norvegicus (rat)) | BDBM50051195 ((2-ferrocenyl)-carbamic acid 3-(1H-imidazol-4-yl)-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universität Berlin Curated by ChEMBL | Assay Description In vitro antagonistic activity of the compound against Histamine H3 receptor on Synaptosomes of rat cerebral cortex. | J Med Chem 39: 1157-63 (1996) Article DOI: 10.1021/jm9507688 BindingDB Entry DOI: 10.7270/Q2SF2V7G | |||||||||||
More data for this Ligand-Target Pair |