BDBM50051296 7-Methoxy-2-phenyl-quinoline-4-carboxylic acid benzylamide::CHEMBL51120

SMILES: COc1ccc2c(cc(nc2c1)-c1ccccc1)C(=O)NCc1ccccc1

InChI Key: InChIKey=ULHFEESQDIXXBS-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50051296   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50051296 (7-Methoxy-2-phenyl-quinoline-4-carboxylic acid ben...) Show SMILES COc1ccc2c(cc(nc2c1)-c1ccccc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C24H20N2O2/c1-28-19-12-13-20-21(24(27)25-16-17-8-4-2-5-9-17)15-22(26-23(20)14-19)18-10-6-3-7-11-18/h2-15H,16H2,1H3,(H,25,27)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Milano Curated by ChEMBL					Assay Description Inhibition of [125I]-MePhe7-Neurokinin B (NKB) binding in human Tachykinin receptor 3 of chinese hamster ovary (hNK-3-CHO) cell membranes.				J Med Chem 40: 1794-807 (1997) Article DOI: 10.1021/jm960818o BindingDB Entry DOI: 10.7270/Q24T6HHB
					More data for this Ligand-Target Pair
Neurokinin 1 receptor (Homo sapiens (Human))	BDBM50051296 (7-Methoxy-2-phenyl-quinoline-4-carboxylic acid ben...) Show SMILES COc1ccc2c(cc(nc2c1)-c1ccccc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C24H20N2O2/c1-28-19-12-13-20-21(24(27)25-16-17-8-4-2-5-9-17)15-22(26-23(20)14-19)18-10-6-3-7-11-18/h2-15H,16H2,1H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity against hTachykinin receptor 1 for the displacement of [3H]-substance P binding from Tachykinin receptor 1 CHO membrane				J Med Chem 39: 2281-4 (1996) Article DOI: 10.1021/jm9602423 BindingDB Entry DOI: 10.7270/Q22J6CJR
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50051296 (7-Methoxy-2-phenyl-quinoline-4-carboxylic acid ben...) Show SMILES COc1ccc2c(cc(nc2c1)-c1ccccc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C24H20N2O2/c1-28-19-12-13-20-21(24(27)25-16-17-8-4-2-5-9-17)15-22(26-23(20)14-19)18-10-6-3-7-11-18/h2-15H,16H2,1H3,(H,25,27)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.33E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity against human Tachykinin receptor 3 for the displacement of [3H]-substance P binding from human Tachykinin receptor 3 CHO membrane				J Med Chem 39: 2281-4 (1996) Article DOI: 10.1021/jm9602423 BindingDB Entry DOI: 10.7270/Q22J6CJR
					More data for this Ligand-Target Pair