BDBM50051678 CHEMBL82038::R-2'-phenyl-7'-[1-phenyl-(1R)-ethyl]spiro[cyclopentane-1,5'-(4',5',6',7'-tetrahydro-3'H-pyrrolo[2,3-d]pyrimidine)]-4',6'-dione

SMILES: C[C@@H](N1C(=O)C2(CCCC2)c2c1nc([nH]c2=O)-c1ccccc1)c1ccccc1

InChI Key: InChIKey=RCBKEDINQSCQRZ-MRXNPFEDSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50051678   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat))	BDBM50051678 (CHEMBL82038 | R-2'-phenyl-7'-[1-phenyl-(1R)-ethyl]...) Show SMILES C[C@@H](N1C(=O)C2(CCCC2)c2c1nc([nH]c2=O)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H23N3O2/c1-16(17-10-4-2-5-11-17)27-21-19(24(23(27)29)14-8-9-15-24)22(28)26-20(25-21)18-12-6-3-7-13-18/h2-7,10-13,16H,8-9,14-15H2,1H3,(H,25,26,28)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Julius-Maximilians-Universität Würzburg Curated by ChEMBL					Assay Description Radioligand binding assay for [3H]-NECA affinity towards adenosine A2A receptor of rat striatum				J Med Chem 39: 2482-91 (1996) Article DOI: 10.1021/jm960011w BindingDB Entry DOI: 10.7270/Q27H1HPH
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50051678 (CHEMBL82038 | R-2'-phenyl-7'-[1-phenyl-(1R)-ethyl]...) Show SMILES C[C@@H](N1C(=O)C2(CCCC2)c2c1nc([nH]c2=O)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H23N3O2/c1-16(17-10-4-2-5-11-17)27-21-19(24(23(27)29)14-8-9-15-24)22(28)26-20(25-21)18-12-6-3-7-13-18/h2-7,10-13,16H,8-9,14-15H2,1H3,(H,25,26,28)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Julius-Maximilians-Universität Würzburg Curated by ChEMBL					Assay Description Radioligand binding assay for [3H]-PIA affinity towards Adenosine A1 receptor of rat cerebral cortical membrane				J Med Chem 39: 2482-91 (1996) Article DOI: 10.1021/jm960011w BindingDB Entry DOI: 10.7270/Q27H1HPH
					More data for this Ligand-Target Pair