BDBM50052565 5-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxylic acid {3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-amide::CHEMBL110968

SMILES: COc1cccc2C(CCCc12)C(=O)NCCCN1CCN(CC1)c1ccccc1OC

InChI Key: InChIKey=LTLCYGQKNCSZNO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50052565   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50052565 (5-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxy...) Show SMILES COc1cccc2C(CCCc12)C(=O)NCCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C26H35N3O3/c1-31-24-13-6-8-20-21(24)9-5-10-22(20)26(30)27-14-7-15-28-16-18-29(19-17-28)23-11-3-4-12-25(23)32-2/h3-4,6,8,11-13,22H,5,7,9-10,14-19H2,1-2H3,(H,27,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity against serotonin 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]8-OH-DPAT as radioligand				J Med Chem 39: 3195-202 (1996) Article DOI: 10.1021/jm960087s BindingDB Entry DOI: 10.7270/Q2GM87ZN
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50052565 (5-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxy...) Show SMILES COc1cccc2C(CCCc12)C(=O)NCCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C26H35N3O3/c1-31-24-13-6-8-20-21(24)9-5-10-22(20)26(30)27-14-7-15-28-16-18-29(19-17-28)23-11-3-4-12-25(23)32-2/h3-4,6,8,11-13,22H,5,7,9-10,14-19H2,1-2H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D2 in rat striatal membrane using [3H]spiroperidol as radioligand				J Med Chem 39: 3195-202 (1996) Article DOI: 10.1021/jm960087s BindingDB Entry DOI: 10.7270/Q2GM87ZN
					More data for this Ligand-Target Pair